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Pharmacy News

Compound Has Potential For New Class Of AIDS Drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs.

Nanotechnology In Reverse Uses Cell To Calibrate Tools
Nanotechnology researchers at UC Davis have shown that they can use a red blood cell to calibrate a sensitive instrument, an atomic force microscope.

Monkey Studies Important For Brain Science
Studies with non-human primates have made major contributions to our understanding of the brain and will continue to be an important, if small, part of neuroscience research, according to a recent review published in the British medical journal, The Lancet.Authors John P.

Study Looks At Predictors Of Late Language Emergence In Toddlers
New research findings from the world's largest study on language emergence have revealed that one in four late talking toddlers continue to have language problems by age 7.

Funding For Development Of OSU Technologies
OSU's Technology Business Assessment Group will fund four faculty research projects for spring 2008. The group identified these one-year projects from a number of excellent proposals submitted in response to a solicitation earlier this spring. Funding for the program is administered by the OSU Office of Intellectual Property Management, and is generated by royalties from OSU-licensed technologies.

Australian Metabolic Syndrome Research Project Receives Grant From International Diabetes Federation
The International Diabetes Federation (IDF) BRIDGES translational research grant program will fund STOP Diabetes, a project to be implemented and studied in Australia. The STOP project is designed to reduce the risk for type 2 diabetes in women by encouraging healthy behaviours.

'Dirt-Powered' Microbial Fuel Cells Developed By Undergraduates To Light Africa
A team composed of Harvard students and alumni was among the winners of the World Bank's Lighting Africa 2008 Development Marketplace competition, held in Accra, Ghana. The innovation, microbial fuel cell-based lighting systems suitable for Sub-Saharan Africa, netted the group a $200,000 prize.

Ning Wong Of Fox Chase Cancer Center Receives ASCO Cancer Foundation Career Development Award
The American Society of Clinical Oncology Cancer Foundation has selected Yu-Ning Wong, M.D., M.S.C.E., of Fox Chase Cancer Center, as one of 13 clinicians to receive a 2008 Career Development Award. Career Development Awards are presented to physicians in their second, third or fourth year as full-time faculty members in an academic setting.

New Formula Connects Optical Quality With Visual Acuity With Potential To Provide Automatic Eyeglasses Prescriptions
For the first time, a study combines measurements of abnormalities in the eye with models for assessing how well an individual can see, meaning it may be possible to program a machine to automatically produce prescriptions for corrective lenses.

Factors In Delaying Or Declining Total Knee Replacement Surgery
A study led by Dr. Ann F. Jacobson, associate professor in Kent State's College of Nursing, unveils the reasons why people may initially choose to postpone but ultimately undergo total knee replacement surgery and emphasizes the need for better patient education before and after the procedure.

World's Largest Conference On Evolution To Be Hosted By University Of Minnesota
University of Minnesota to host world's largest conference on evolution; author, columnist Olivia Judson headlines.More than 1,400 of the world's top experts on evolution will gather in Minnesota June 20 through 24 for "Evolution 2008," the world's largest annual gathering of evolutionary biologists.

Analysis: Control Reduces Cardiovascular Risk By 42%
Results of a new analysis of the Treating to New Targets (TNT) study show that intensive low-density lipoprotein (LDL) cholesterol-lowering in patients with stable coronary heart disease (CHD) whose systolic blood pressure was less than 140 mmHg reduced the risk of major cardiovascular events, includ

Prospective Study Of The Long-Term Effects Of Shock Wave Lithotripsy On Renal Function And Blood Pressure
UroToday.com - The debate regarding the long-term effects of SWL on patient hypertension and diabetes continues.These researchers from Egypt prospectively randomized 100 patients with a single, 2 cm or less renal stone and similar BMI's, treated with unilateral SWL on an electrohydraulic (Dornier MFL 5000) or an electromagnetic (Dornier Lithotripter S) lithotripter unit.

Robot-Assisted Laparoscopic Ureteroureterostomy: Description Of Technique
UroToday.com - This study out of Boston Children's by Passerotti, et al described the group's technique utilizing robotics for ureteroureterostomy in patients with mid ureteral obstructions. The group had 3 patients, 2 who were boys and 1 girl with their ages being 4.7, 9.6 and 14.3 years. These patients all had mid ureteral strictures and obstruction.

Bone Drug Could Help Prevent The Spread Of Breast Cancer
Maintaining bone density could be a key to decreasing the spread of cancer in women with locally advanced breast cancer, according to research at Washington University School of Medicine in St. Louis.Bones are common sites for the spread, or metastasis, of breast cancer.

Disabling Mouse Enzyme Increases Fertility
Changing the sugars attached to a hormone produced in the pituitary gland increased fertility levels in mice nearly 50 percent, a research group at Washington University School of Medicine in St. Louis has found. The change appears to alter a reproductive "thermostat," unveiling part of an intricate regulatory system that may one day be used to enhance human fertility.

Only About 1 In 10 Adult Americans Are Health Literate
Just 12 percent of America's 228 million adults have the skills to manage their own health care proficiently, according to the latest News and Numbers from the Agency for Healthcare Research. These skills, known collectively as health literacy, describe people's person's ability to obtain and use health information to make appropriate health care decisions.

New Treatment Implications For Ovarian Cancer Unveiled
New research findings from a top clinical investigator at The Cancer Institute of New Jersey (CINJ) indicate the potential for more targeted treatment of ovarian cancer, which is expected to claim more than 15,000 lives nationwide this year, with 480 in New Jersey.

Fibroids Common, But Women Have Options
Small fibroids located just beneath the lining of the uterus (submucosal) are more likely to move to the endometrial cavity after uterine artery embolization (UAE) but usually don't cause major complications, according to a new study.The study included 49 patients with 140 fibroids who underwent an MRI examination before and after UAE. The study found that 39 of these were submucosal.

Scientist Unravels Deadly Pathogens
A scientist in the Department of Biomedical Engineering at the University of Virginia Health System has deciphered the metabolic properties of two dangerous pathogens discovering how they thrive and which genes, when knocked out, cause them to weaken. Jason Papin, Ph.D.

Suicide Prevention Group Delivers Much Needed Message To Pennsylvania's Elderly
This month, in recognition of National Mental Health Month and Older Pennsylvanians Month, Feeling Blue Suicide Prevention Council (SPC) will offer an important message to senior citizens through a public service announcement.

World AIDS Vaccine Day 2008
Twenty-five years since the discovery of HIV, the world has made considerable advances in addressing the AIDS pandemic. Scientists have learned a tremendous amount about HIV, perhaps more than any other pathogen, and have developed more drugs to treat AIDS than all other viral diseases combined. But this progress is not enough.

AIDS Action Urges Everyone To Help End The AIDS Epidemic By Being Part Of The Search For An HIV Vaccine
Twenty-six years into the AIDS epidemic, someone is newly infected with HIV every 13 minutes in the U.S.

Boston Scientific Announces FDA Approval Of New Heart Failure Lead
Boston Scientific Corporation (NYSE: BSX) announced U.S. Food and Drug Administration (FDA) approval of its ACUITY(R) Spiral left ventricular lead for use with cardiac resynchronization therapy defibrillators (CRT-D) and cardiac resynchronization therapy pacemakers (CRT-P), both of which treat heart failure.

Nexavar Significantly Improves Overall Survival By 47 Percent In Asia Pacific Liver Cancer Study
Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) announced that Nexavar(R) (sorafenib) tablets significantly improved overall survival by 47.3 percent (HR=0.68; p-value=0.014) in patients in the Asia-Pacific region with advanced hepatocellular carcinoma (HCC), or primary liver cancer versus those receiving placebo.

First Electrophysical Recording Of Sleep In A Wild Animal
In the first experiment to record the electrophysiology of sleep in a wild animal, three-toed sloths carrying miniature electroencephalogram recorders slept 9.63 hours per day - 6 hours less than captive sloths did, reports an international team of researchers working on the Smithsonian Tropical Research Institute's Barro Colorado Island in Panama.

New Gene Methylation Test For Prostate Cancer Available
Veridex, LLC announced that its licensing collaborator, Laboratory Corporation of America Holdings (LabCorp), has commercially launched a new gene methylation test for prostate cancer. The new assay uses the biological specificity of 'DNA methylation' in prostate cancer, detecting the methylation of the gene GST-Pi.

Pharmacopeia's First-in-Class Investigational Therapy PS433540 Achieves Statistically Significant Reductions In Blood Pressure In Hypertensive Patient
Pharmacopeia (Nasdaq: PCOP), an innovator in the discovery and development of novel small molecule therapeutics, announced that PS433540, its first-in-class Dual Acting Receptor Antagonist (DARA), showed statistically significant blood pressure reductions in a Phase 2a study in patients with mild to moderate hypertension.

Significant Anti-Tumor Activity Of NKTR-102 In Patients With Refractory Solid Tumors; Interim Data Published In ASCO 2008 Proceedings
Nektar Therapeutics (Nasdaq: NKTR) announced initial results from a Phase 1 study of NKTR- 102, PEGylated irinotecan. The data shows significant anti-tumor activity in patients with refractory solid tumors.

Rosetta Genomics To Present Multiple Posters At The 44th Annual Meeting Of The American Society Of Clinical Oncology (ASCO)
Rosetta Genomics Ltd. (Nasdaq:ROSG), a leader in the development of microRNA-based diagnostics and therapeutics, announced that it will present multiple posters at the upcoming ASCO annual meeting in Chicago. The company also has three publication only abstracts available on ASCO's website. The event will take place from May 30 to June 3 at the McCormick Place, Chicago, Illinois.

Pulmo BioTech Announces Details Of The Methodology For Its Phase I Human Trials
Pulmo BioTech Inc. (OTC Bulletin Board: PLMO.OB) has announced details of the methodology and purpose of its Phase I Human Trials with its PulmoBind Molecular Imaging technology for the diagnosis of Pulmonary Embolism and Pulmonary Hypertension. The work will be carried out by the Pulmo BioTech subsidiary, PulmoScience Inc.

Memory Pharmaceuticals Highlights Progress With Key Programs At Its R&D Day
Memory Pharmaceuticals Corp. (Nasdaq: MEMY) announced progress with several key development programs at its R&D Day meeting with the investment community. The Company reported new clinical data for MEM 1414, its lead PDE4 inhibitor, demonstrating the compound's CNS activity in humans.

Bayer Schering Pharma Starts Global Awareness Campaign - Mastering MS
The results of an international survey presentedby Bayer Schering Pharma shows that many people face the same fears andconcerns when they are first diagnosed with multiple sclerosis (MS). In thesurvey, 71 percent of people with MS had at least one concern about how thedisease would affect their relationships; 64 percent said being diagnosedhad a negative impact on their career.

AMA Congratulates The Flying Doctors On 80 Years Of Saving Lives, Australia
The Australian Medical Association congratulated The Royal Flying Doctor Service (RFDS) on 80 years of providing emergency and primary health care to people in the bush.The RFDS celebrates its 80th anniversary today.AMA President, Dr Rosanna Capolingua, said that without the extensive health care network flown in by the RFDS, much of outback and rural Australia would be left exposed.

Recurring Symptoms Experienced By Nearly 40 Percent Of GERD Patients Taking PPIs
Despite daily use of doctor-recommended proton pump inhibitors (PPIs) to control gastroesophageal reflux disease (GERD) symptoms, nearly 40 percent of patients who take them continue to experience breakthrough, which is a return of GERD symptoms, such as acid regurgitation and heartburn.

Combination Of Genomics And Proteomics Yields A Surprising Finding: Silencing Foreign DNA In Bacteria
Compared to humans, bacteria have a much tidier genome. The tiny microorganisms pack their genes closely together, and don't carry around a lot of extraneous DNA, so-called junk DNA that fills in the gaps between genes. Some 90 percent of the complete genome sequence of the bacteria E.

4th International AMAM Symposium: Animal Behavior Turned Into Robots And More
Building a machine that moves like a cockroach, salamander, fish or another creature is no easy task.

In Patients With Metastatic Prostate Cancer Therapeutic Vaccine Prolongs Survival And Improves Quality Of Life
A new prostate cancer vaccine may give hope to men with metastatic prostate cancer by enabling their immune systems to fight the disease. Researchers from the University of Iowa presented data on the adenovirus/PSA (Ad/PSA) vaccine during the Annual Scientific Meeting of the American Urological Association in Orlando.

Current Regenerative Medical Techniques Hold Great Promise For Bladder Regeneration
Bladder regeneration via a neo-bladder replacement may prove to be effective in humans.

Baseline PSA Reading A Reliable Prostate Cancer Predictor For Up To 30 Years
Premalignant phases of prostate cancer occur over long periods of time and a single prostate-specific antigen (PSA) reading taken at age 44-50 can help predict prostate cancer diagnosis up to 30 years subsequently, according to updated data from researchers in New York and Malmo, Sweden. The findings expand the previously established baseline age-to-diagnosis interval.

Active Surveillance A Viable Option For Low-Risk Prostate Cancer
Active surveillance remains a viable option for low-risk, localized prostate cancer, according to two studies presented during the Annual Scientific Meeting of the American Urological Association (AUA), yet researchers point out a strong need for regular monitoring and development of stronger clinical predictors of progression.

Obstructive Sleep Apnea-Related Brain Deficits Beaten By Green Tea Compounds
Chemicals found in green tea may be able to stave off the cognitive deficits that occur with obstructive sleep apnea (OSA), according to a new study published in the second issue for May of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

Stroke Patients At Greater Risk For Falls
Stroke patients are at high risk for falls and subsequent injuries after leaving the hospital, but prevention programs may reduce this risk, New Zealand researchers reported in Stroke: Journal of the American Heart Association."People who have had a stroke fall almost twice as often as people who haven't had a stroke," said Ngaire Kerse, Ph.D.

Questioning The Risk Of Death From Higher Salt Intake
Contrary to long-held assumptions, high-salt diets may not increase the risk of death, according to investigators from the Albert Einstein College of Medicine of Yeshiva University. They reached their conclusion after examining dietary intake among a nationally representative sample of adults in the U.S.

Americans Must Consider Cost And Effectiveness When Comparing And Choosing Medical Interventions
The American College of Physicians (ACP) has proposed a means to improve physician and patient access to and use of information about clinical and cost-effectiveness when comparing medical products, procedures and services.

ACP, ACP Foundation Diabetes Initiative Plans For 2 More Years
The Diabetes Initiative of the American College of Physicians (ACP) and the ACP Foundation released new information on the first three years of its project to improve diabetes care primarily through special efforts targeting physicians' practices.The Initiative was funded in 2005 by an unrestricted educational grant from Novo Nordisk, Inc.

About 39% Of IDUs Living In Spain Are HIV-Positive, IHRA Report Says
As many as 39% of the approximately 84,000 injection drug users living in Spain are HIV-positive, and as many as 73% are living with hepatitis C, according to a recent report by the International Harm Reduction Association, Spain's El PaÃs reports.

California Gov. Schwarzenegger Releases Revised Budget That Includes Additional Cuts To Health Care
California Gov. Arnold Schwarzenegger (R) on Wednesday released a revised fiscal year 2009 state budget that includes deeper cuts to health and social service programs than previously proposed, the Sacramento Bee reports (Yamamura, Sacramento Bee, 5/15). Schwarzenegger added $1.

Reps. Langevin, Shays Promote Bipartisan Health Care Reform Bill
Reps. Jim Langevin (D-R.I.) and Christopher Shays (R-Conn.) have begun to "position themselves for a major debate on health care reform in 2009 by laying down a marker this year," The Hill reports.Langevin and Shays support legislation, which Langevin first introduced in 2004, that would provide U.S. residents with access to the same level of health insurance as members of Congress.

Embryonic Parasitic Twin Removed From 9-Year-Old Girl's Stomach
Doctors at the General Hospital in the Greek city of Larissa said yesterday, Thursday, that they had successfully removed an embryonic parasitic twin from the stomach of a 9-year-old girl.The girl, whose family asked that she not be named, was suffering from stomach pains, which the doctors established were due to a tumour growing on the right side of her belly.

VOA News Publishes Several HIV/AIDS-Related Articles
VOA News on Tuesday published several articles about HIV/AIDS in Africa. Summaries appear below."African Countries Seek Common Approach Against HIV/AIDS": Leaders of several African countries are proposing a common African approach to fighting the spread of HIV/AIDS after the most recent 2007 statistics show that 24.4 million people on the continent are living with the disease.

New York City Would Lose $1B For Physician Training Under Proposed Medicaid Cuts
New York City hospitals could lose more than $1 billion in state and federal funds for physician training as a result of federal Medicaid changes scheduled to take effect May 25, according to an analysis released Tuesday by the city's Independent Budget Office, the New York Times reports.

Former Presidential Candidate Edwards Endorses Obama
Former Democratic presidential candidate and former Sen. John Edwards (N.C.) on Wednesday at a Grand Rapids, Mich., rally announced his endorsement of Democratic presidential candidate Sen. Barack Obama (Ill.), in part because of his support for an expansion of health insurance to more residents.

Cancer Awareness Efforts Need To Reach All Racial And Ethnic Groups, Opinion Piece Says
Awareness of early cancer screening and detection methods, and "better access to cancer prevention information" need to be expanded to all California residents, particularly minorities, California Assembly member SandrÃ© Swanson (D) writes in a San Francisco Chronicle opinion piece.

World Bank Announces Plan To Implement Long-Term Development Projects To Fight HIV/AIDS In Africa
The World Bank on Wednesday announced a four-year plan to tackle HIV/AIDS in Africa that shifts its mission from providing emergency relief to implementing long-term development projects, Reuters reports (Wroughton, Reuters, 5/14).

FDA Should Review Potentially Deceiving Television Advertisements For Johnson & Johnson Stent, NEJM Opinion Piece Says
Television advertisements for Johnson & Johnson's drug-coated Cypher stent might deceive consumers and should be reviewed by FDA, according to an opinion piece published Wednesday in the New England Journal of Medicine, the New York Times reports.

Malaysia Considers Providing Sex Education To Participants In National Service Program
Officials in Malaysia are considering providing sex education to high school graduates who enter the country's national service program, according to Abdul Hadi Awang Kechil, director general of the National Service Department, the AP/Google.com reports. According to the AP/Google.

Racial Disparities In Diabetes Control Not Solely Linked To Lower Treatment Adherence Among Blacks, Study Finds
Lower diabetes treatment adherence among blacks does not fully explain racial disparities in diabetes control, according to a study published in the journal Diabetes Care, Reuters Health reports. Blacks with type 2 diabetes tend to have more problems controlling their blood sugar than whites and also are at a higher risk of developing complications from diabetes, according to Reuters Health.

Health Care Leaders Discuss Ways To Improve Health Care In New Interview Series
"Viewpoints: The Health Care Debate": Kaiser Family Foundation: The new interview series, led by Kaiser Family Foundation Vice President Jackie Judd and kaisernetwork.org Managing Editor Jill Braden Balderas, examines the diversity of perspectives on the problems and potential solutions for improving health care in the U.S.

Inspectors Often Overlook Serious Deficiencies At U.S. Nursing Homes, GAO Report Finds
State nursing home inspectors miss or minimize deficiencies -- such as malnutrition, severe bedsores, overuse of medications and abuse -- that pose a serious, immediate threat to patients, according to a report scheduled for release on Thursday by the Government Accountability Office, the New York Times reports.

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